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Furthermore, this antibody has been shown to induce the lysis of membrane-bound TNF-alpha (mTNF-α)—expressing cells through complement activation or cytotoxicity
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In the green pathway, the diffusible intracellular IP3 messenger is a ligand for a Ca 2+ -permeable ion channel, the IP3 receptor (IP3R), on the endoplasmic reticulum (ER) (Figure 5)
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