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Monoamine oxidases degrade neurotransmitters and are essential for normal brain metabolism, but an age-related increase in their activity can deplete catecholamine neurotransmitters (dopamine, norepinephrine, and adrenaline), which impairs mental function [144,145]
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Moreover, prolonged exposure to oxidative stress impacts the condition of keratinocytes, leading to alterations in skin barrier function and cell death
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