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Because it does not impact systemic growth factor pathways, it avoids issues like fluid retention or insulin disruption

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19 Other health benefits of UA were seen in age-associated diseases such as cardiac 20 , 21 and neurodegenerative disorders 22 and osteoarthritis, 23 as well as in inflammatory bowel diseases 24 and acute kidney injury.25, 26, 27 From a clinical translational perspective, UA has been shown to be safe and bioavailable in humans and to enhance mitochondrial gene expression in the skeletal muscle and improve cellular health after a 4-week oral administration in sedentary older adults