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This is because of the ability of nitric oxide to react with biomolecules or with other free radicals e.g., superoxide anion, yielding the highly reactive peroxynitrite radical capable of evoking the oxidation of important cellular biomolecules (Moncada et al., 1991[48]
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Anther drug, JLX001, the dihydrochloride of cyclovirobuxine D (CVB-D) also has protective effects over the BBB
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