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The in silico analysis demonstrated a strong affinity of amlodipine for αA, αG, and SI, which may explain antiglycation effects in vivo
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Subsequently, roGFP2-iL was fused behind human GRX1 to generate GRX1-roGFP2-iL (Figure 1C) to ensure specificity of the novel probe for E GSH similar to other roGFP variants used before (Gutscher et al., 2008
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