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1 Beyond these local reactions, other commonly reported effects include: Temporary nausea, more common with oral dosing 1 Headache or dizziness (uncommon) Occasional vivid dreams in the first week 1 Preclinical work shows a plateau in healing response above roughly 10 mcg/kg, so higher doses rarely improve outcomes and mainly raise cost and exposure risk

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MR analyses in Zhou and Hyppönen (Reference Zhou and Hyppönen39) and Kwok et al