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In addition, anti-retroviral treatment (ART) along with Spirulina showed more beneficial effects than ART coupled to soyabeans (increased CD4 cell counts and decreased viral load in Spirulina group)
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To further experimentally validate that these residues are involved in binding, we performed mutagenesis studies on the conserved K16, K17, K23, G24, and K25 residues that are predicted in our MD simulation to lie at the binding interfaces
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