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Several factors, including molecular mass, chemical nature, esterification, glycosylation, and botanical source, influence the uptake of dietary flavonoids [60]
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However, Margaret McCarthy’s lab has shown that drug-mediated inhibition of prostaglandin synthesis (as is accomplished by acetaminophen) in laboratory rats during “a time sensitive window in early postnatal life” not only results in significant long-term modifications to brain development and morphology but also leads to decreased social interactions and reduced sensory function in male but not female animals
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