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Nuclear acetyl-CoA is derived from citrate, which is generated in the mitochondria by the TCA cycle, transported out of the mitochondria, and converted back to oxaloacetate (OAA) and acetyl-CoA by nuclear ACL [73]
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van Zanten AR, Sztark F, Kaisers UX, Zielmann S, Felbinger TW, Sablotzki AR, De Waele JJ, Timsit JF, Honing ML, Keh D, Vincent JL, Zazzo JF, Fijn HB, Petit L, Preiser JC, van Horssen PJ, Hofman Z: High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial
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