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Typical cycle structures by condition: Acute injuries (sprains, minor strains): 4–6 weeks Chronic tendinopathy or joint issues: 6–8 weeks Post-surgical recovery: 8–12 weeks Gut healing (oral): 6–8 weeks A 4–6 week off-period between cycles allows receptor sensitivity to reset, as consecutive cycles without a washout may lead to receptor desensitization and reduced efficacy

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Amylin, also known as islet amyloid polypeptide or IAPP, is a peptide hormone produced by pancreatic beta-cells and secreted alongside insulin, downstream of nutrient sensing