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The secondary injury, which could start within minutes post-injury, a delayed complex process leading to chronic neuropathological changes, including metabolic perturbation, neuroinflammation, oxidative stress, diffuse axonal injuries, neurovascular changes, and could ultimately involve neurodegenerative process, depending on the severity of injury (Greve and Zink, 2009
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This section focuses specifically on the chemical and structural modifications of major biomolecules caused by photooxidative stress under blue light (Figs
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