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However, the most common dermatological manifestation is hyperpigmentation [2], which often occurs in combination with systemic findings, including macrocytic anemia, pancytopenia, and subacute combined degeneration of the cord (SCD) [3]
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Remarkably, NNMTi-treated aged sedentary mice showed ~ 40% greater grip strength than sedentary controls, while aged exercised mice only showed a 20% increase relative to controls
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