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Finally, to investigate the importance of IGF1R in mediating the bone and growth abnormalities in Gif –/– (F2) mice, we treated these mice with either vehicle [ Gif –/– (F2) /VEH] or taurine plus OSI906 (50 mg/kg BW/d) [ Gif –/– (F2) /TAU+OSI906] from P16 onward
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