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AMPK acts as an energy sensor and promotes autophagy by phosphorylating MTOR complex 1 (MTORC1), ULK1 (unc-51 like autophagy activating kinase 1), and the BECN1 (beclin 1) component of PIK3C3/VPS34 (phosphatidylinositol 3-kinase catalytic subunit type 3) complexes [166–169]
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