glutathione aromatase Endometriosis Immunosenescence: signaling pathways, diseases

Immunosenescence: signaling pathways, diseases and therapeutic targets | Signal Transduction and Targeted Therapy

They suggested that the hydroxyl group of Thr391 (in EcGGT) acts as a nucleophile for proteolytic cleavage of scissile peptide bond with the preceding residue Gln390

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The molecule of curcumin, 1,7-bis(4-hydroxy-3- methoxyphenyl)-1,6-heptadiene-3,5-dione (diferuloylmethane), when orally administrated, is quite stable in the acidic pH of the stomach (Wang et al., 1997), but it undergoes extensive first pass metabolism, is conjugated in the liver, and excreted in the feces