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glutathione redox control antioxidants and redox fitzpatrick 2012 Glutathione-driven decisions in cell survival death Magnolia - For the
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Protein carbonylation represents a non-enzymatic modification and involves the covalent introduction of carbonyl groups (–C=O), typically aldehydes or ketones, into amino acid side chains (primarily proline, arginine, lysine, and threonine) through two major pathways: direct oxidation by ROS and secondary modification via lipid peroxidation-derived aldehydes MDA and 4-HNE [89]
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