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Several critical pathways have been implicated to be regulated by free radicals, including axes controlling cell proliferation such as the phosphatidylinositol 3 kinase (PI3K)/protein kinase B (AKT) pathway, cell death programs such as apoptosis, and inflammation such as NLRP3 inflammasome mediating signaling
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This physiological adaptation likely contributes to the observed body weight increase in FOS + GOS-administered mice (Fig
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