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one study of meta-analysis in 2020 incorporating 7 RCTs of OSF reported that lycopene is only effective in refining maximum mouth opening without improving other symptoms ( 2 Efficacy of lycopene in digestive precancerous lesions In recent years, numerous studies have evaluated the efficacy of lycopene in managing precancerous lesions of the digestive tract, and relevant clinical or animal studies over the last 10 years have been summarized and shown in Table 1

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