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In support of CE hydrolysis of LDL increasing the atherogenicity of LDL, human macrophages have been shown to take up LDL modified by hydrolysis with neutral cholesteryl ester hydrolase (nCEH) at a rate exceeding that of oxLDL or acLDL (Bhakdi et al., Oxidative modification of LDL Oxidation of LDL is proposed to contribute to foam cell formation by virtue of oxLDL being a ligand for scavenger receptors
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doi: 10.1016/S1473-3099(19)30312-3 372 ChenSCPerfectJColomboALCornelyOAGrollAHSeidelDet al
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